
A giant cell is a mass formed by the union of several distinct cells (usually macrophages), often forming Granuloma. It can arise in response to an infection, such as from tuberculosis, herpes, or HIV, or foreign body. These multinucleate giant cells also known as (MGCs) are cells of monocyte or macrophage lineage fused together. Types include: Al...
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http://en.wikipedia.org/wiki/Giant_cell

<pathology> A cell of large size, often with many nuclei. They are multinucleated masses produced by the fusion of many cells. ... They are often associated with viral infections. In AIDS, they are induced when the envelope glycoprotein of HIV binds to the CD4 antigen of uninfected neighboring T4 cells. The resulting syncytium leads to cell d...
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a large, multinucleate cell. The most common type is the megakaryocytes found normally in bone marrow. Abnormal types are formed by coalescence and fusion of macrophages in tuberculosis; cells occurring in other infectious granulomas; large cells that surround foreign bodies; and certain cancer cells.
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A multi-nucleate mass of protoplasm formed by coalescence of several adjacent plant cells. Also called a syncytium. Found in plants infected by certain nematodes.
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Type: Term Definitions: 1. a cell of large size, often with many nuclei.
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http://www.medilexicon.com/medicaldictionary.php?t=15623
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